Mechanism of naltrexone

Client: The C3 Foundation.

My responsibilities: Project management, instructional design (storyboarding, mock-ups, prototypes, full build), subject-matter research and expertise, storyboard writing editing, graphic design , custom illustration, 3D modelling and animation.

Tools used: Blender 3D, Adobe Illustrator and Photoshop, Google Docs, Miro.

Duration: Six months.

Summary

The challenge

In a project requiring the development of a high-quality medical animation explaining the mechanism of naltrexone for alcohol use disorder, I faced challenges due to a very limited budget and a tight project timeline. The task was to create an impactful animation despite the constraints, emphasising the critical aspects of the naltrexone mechanism for a general audience.

The solution

To address the limitations, I designed quick prototypes featuring essential organs involved in the medical interaction, such as the stomach, liver, circulatory system, and neuron surface of the brain. Using an eye-catching colour scheme, I drew attention to key elements and facilitated stakeholder involvement by allowing them to choose from these prototypes.

To optimise resources, I strategically allocated the most intricate animation effects to critical components, particularly focusing on the neuron surface. Leveraging Python scripting, I efficiently animated large groups of objects via code, including naltrexone and endorphin molecules.

I implemented a transparent and collaborative approach by providing stakeholders with twice-weekly working drafts for review, feedback, and iteration. This ensured continuous refinement and alignment with the project goals.

Video: View the completed project

My process

Planning

To initiate the animation project in Blender 3D, I commenced with a comprehensive planning phase. Utilising a mind map, I systematically compiled a full spectrum of major ideas, thoughts, and possibilities. This visual tool facilitated the exploration of various concepts and the effective organisation of ideas. Subsequently, I analysed and synthesised the ideas from the mind map into detailed notes and formal documentation. This documentation was essential for sharing with stakeholders, ensuring a clear understanding of the project’s scope and objectives from the outset.

Text storyboard

The text storyboard was meticulously crafted from scratch, grounded in rigorous scientific research. My primary focus was on conveying accurate scientific explanations while scrupulously avoiding the provision of medical advice. This approach ensured that the content remained reliable and based on well-established scientific principles. Regular stakeholder involvement was integral throughout this process, facilitating continuous feedback and alignment with the project's goals. Their input was invaluable in refining the storyboard to meet both educational standards and stakeholder expectations.

Video: Basic animated visual storyboard [28 seconds]

For the basic visual storyboard, I employed simple 2D animation tools to create a preliminary visual representation of the animation. This approach was significantly faster than utilising 3D animation tools, yet effectively demonstrated all major components and animations. The simplicity of the 2D animations provided a clear and concise overview of the project's visual direction, enabling stakeholders to easily comprehend and provide feedback early in the development process.

3D design and planning

During the 3D design and planning phase, I sourced free models whenever possible to optimise resources and efficiency. Utilising real 3D structures of known protein molecules added a layer of authenticity and accuracy to the project. I prioritised creating the models first and sought stakeholder feedback before committing time to detailed design and coloration. This iterative process ensured the models met the project’s requirements and stakeholders' expectations prior to proceeding. The final design maintained a simple illustrative style rather than pursuing photorealism, achieving a balance between clarity and scientific precision.

Reflections and learnings

Adopt a simple graphical style that combines accuracy and elegance

Another crucial insight from this project is the effectiveness of adopting a simple graphical style that balances accuracy with elegance. A straightforward illustrative approach can convey complex scientific concepts clearly and effectively, without the need for overly detailed or photorealistic designs. This method not only enhances the visual appeal and accessibility of the content but also reduces the time and resources required for creation. By focusing on clarity and aesthetic simplicity, the project can maintain scientific integrity while engaging the audience effectively.

Plan and build larger and more complex in a modular fashion

The experience gained from this project underscores the value of planning and constructing larger and more complex projects in a modular fashion. Breaking down the project into smaller, manageable components allows for more precise planning and easier implementation. This approach facilitates iterative development, where each module can be developed, reviewed, and refined independently before integrating into the larger whole. It also enables more effective problem-solving and adjustments throughout the development process, leading to a more robust and adaptable final product.

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